According to the New York Times, David Ortiz and Manny Ramirez were both listed on the infamous 2003 steroid list that also includes Yankee slugger Alex Rodriguez:

Manny Ramirez and David Ortiz, the sluggers who propelled the Boston Red Sox to end an 86-year World Series championship drought and to capture another title three years later, were among the roughly 100 Major League Baseball players to test positive for performance-enhancing drugs in 2003, according to lawyers with knowledge of the results.

If this is true about Ortiz, it is a real shocker. I'm not surprised about Manny, but with Ortiz it goes back to everything he was saying. He said he was clean, he said he never did anything illegal. I think we all believed him. Of course with his struggles this season, it  may have said, "hey, I'm off the juice," but how are we supposed to know?

If this is true, this is quite sad.